Who is weight-loss medication not suitable for?

Weight loss medication is not suitable for everyone. People with certain medical conditions, a BMI that is too low, or who are taking specific other medications may not be eligible. A doctor always assesses on an individual basis whether treatment is medically justifiable. The questions below provide an overview of the most important contraindications and conditions surrounding weight loss medication.

Which medical conditions preclude the use of weight loss medication?

Various medical conditions make the use of weight-loss medication unsuitable or unsafe. In the case of GLP-1 medication, known contraindications include a personal or family history of certain thyroid disorders, a history of pancreatitis, and severe stomach or bowel problems. People with severe kidney or liver disease are also generally not eligible.

In addition, psychological disorders play a role. In people with an active eating disorder, such as anorexia or bulimia, weight-loss medication is in most cases not appropriate. The same applies to people with certain hormonal disorders that affect weight and for whom a different treatment is necessary.

It is important to understand that this list is not exhaustive. A doctor assesses a person's entire medical situation before a treatment is approved. What is safe for one person may be irresponsible for another. Always consult a doctor for an individual assessment.

Can pregnant women or women who are breastfeeding use weight-loss medication?

No. Pregnant women and women who are breastfeeding must not use weight-loss medication. GLP-1 medication is contraindicated during pregnancy because of potential risks to the development of the unborn child. Use is also discouraged during the breastfeeding period, as insufficiently is known about the effects on the infant.

Women who wish to become pregnant are generally advised to stop using GLP-1 medication well in advance of a planned pregnancy. The exact recommended period varies depending on the specific medication and situation. A doctor can provide personal advice on this based on individual circumstances.

Weight loss during pregnancy is medically considered undesirable, regardless of the method. The focus during that period is on a healthy weight gain appropriate for the pregnancy, not on losing weight.

From what BMI or age are you eligible for weight-loss medication?

For most forms of weight loss medication a minimum BMI applies as a condition. In standard medical guidelines, GLP-1 medication is generally used at a BMI of 30 or higher, or at a BMI of 27 or higher in combination with weight-related conditions such as type 2 diabetes or high blood pressure. At a lower BMI, use is not medically justified.

Regarding age, weight-loss medication is in most cases only prescribed to adults aged 18 and over. For young people under 18, safety and effectiveness have been insufficiently researched for regular use outside of specialised care.

An upper age limit does not exist in an absolute sense, but in older patients a doctor carefully weighs the benefits and risks. Factors such as kidney function, medication use and general health play a greater role the older someone is. BMI is therefore a starting point for assessment, but never the only criterion.

Which medicines can interact with weight-loss medication?

Weight-loss medication, and GLP-1 medication in particular, can interact with other medicines. The most relevant category is medicines that affect blood sugar levels, such as insulin and certain diabetes medications. Combining them can lead to blood sugar levels becoming too low, which entails medical risks.

Additionally, GLP-1 medication slows down gastric emptying. This can affect the absorption of other medicines, particularly agents for which a stable and predictable absorption is important. Think of certain antibiotics, contraceptive pills, or blood thinners. The timing of administration can be relevant in such cases.

Thyroid medication and certain treatments for epilepsy also require extra attention when used concurrently. A doctor and pharmacist review a patient's complete medication history before treatment is initiated. It is therefore essential to be completely honest and thorough during the intake about all medicines a person is taking, including over-the-counter products and supplements.

What happens if you use weight-loss medication anyway while you are not eligible for it?

Using weight-loss medication without medical eligibility carries serious health risks. Side effects such as nausea, vomiting and gastrointestinal problems are more common in people for whom the medicine is not suitable. In people with certain conditions, more severe complications can occur, such as inflammation of the pancreas or kidney function issues.

Aside from the direct health risks, there is also the issue of uncontrolled use. Weight-loss medication obtained without medical assessment, for example via foreign websites or informal channels, offers no guarantee of quality, dosage or authenticity. The risks of counterfeit or incorrectly dosed medication are significant.

Finally, the effect without medical supervision is often disappointing. Weight-loss medication works best as part of a broader programme, in which lifestyle, nutrition and medical monitoring play a role. Without that context, the chance of a sustainable result is smaller, while the risks are greater.

How Wellumo helps with the responsible use of weight-loss medication

Wellumo offers a medically sound pathway for people who want to explore whether weight-loss medication is suitable for them. The process is completely online and discreet, but never without a medical assessment. This is how it works:

• Medical Intake A comprehensive questionnaire is used to map out health history, medication use and personal circumstances.
• Assessment by a BIG-registered doctor: A doctor independently assesses whether a treatment is medically appropriate and responsible. Not everyone is eligible.
• Transparent information Prices and the course of the process are clearly communicated in advance, with no hidden costs.
• Discreet delivery Upon approval, medication is discreetly delivered to your home via a certified pharmacy.
• Support throughout the process: Dutch doctors guide patients digitally during the course of treatment.

Do you want to know if you are eligible for treatment? Start the Medical intake at Wellumo and have a doctor assess your situation. Do you have questions first? View How Wellumo works of neem Contact us for more information.